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Mapping the alterations in glutamate with GluCEST MRI in a mouse model of dopamine deficiency

Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI was used to measure metabolic changes in mice treated with 1-methyl-4-phenyl1,2,3,6-tetrahydropyridine (MPTP) by mapping regional cerebral glutamate. The GluCEST contrast following MPTP treatment was correlated with (1)H MR spectroscopy,...

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Publicat a:J Neurochem
Autors principals: Bagga, Puneet, Crescenzi, Rachelle, Krishnamoorthy, Guruprasad, Verma, Gaurav, Nanga, Ravi Prakash Reddy, Reddy, Damodar, Greenberg, Joel, Detre, John A., Hariharan, Hari, Reddy, Ravinder
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077646/
https://ncbi.nlm.nih.gov/pubmed/27529288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13771
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