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A mathematical model of osteoclast acidification during bone resorption
Bone resorption by osteoclasts occurs through the creation of a sealed extracellular compartment (ECC), or pit, adjacent to the bone that is subsequently acidified through a complex biological process. The low pH of the pit dissolves the bone mineral and activates acid proteases that further break d...
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Publicado no: | Bone |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5077641/ https://ncbi.nlm.nih.gov/pubmed/27650914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.09.007 |
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