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A mathematical model of osteoclast acidification during bone resorption

Bone resorption by osteoclasts occurs through the creation of a sealed extracellular compartment (ECC), or pit, adjacent to the bone that is subsequently acidified through a complex biological process. The low pH of the pit dissolves the bone mineral and activates acid proteases that further break d...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Marcoline, Frank V., Ishida, Yoichi, Mindell, Joseph A., Nayak, Smita, Grabe, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077641/
https://ncbi.nlm.nih.gov/pubmed/27650914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.09.007
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