Acidification of the Osteoclastic Resorption Compartment Provides Insight into the Coupling of Bone Formation to Bone Resorption

Patients with defective osteoclastic acidification have increased numbers of osteoclasts, with decreased resorption, but bone formation that remains unchanged. We demonstrate that osteoclast survival is increased when acidification is impaired, and that impairment of acidification results in inhibit...

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Hlavní autoři: Karsdal, Morten A., Henriksen, Kim, Sørensen, Mette G., Gram, Jeppe, Schaller, Sophie, Dziegiel, Morten H., Heegaard, Anne-Marie, Christophersen, Palle, Martin, Thomas J., Christiansen, Claus, Bollerslev, Jens
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2005
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Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602325/
https://ncbi.nlm.nih.gov/pubmed/15681830
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