Congenital hypothyroid goiter with deficient thyroglobulin. Identification of an endoplasmic reticulum storage disease with induction of molecular chaperones.

Recent advances in understanding the molecular pathogenesis of congenital hypothyroid goiter in cog/cog mice, have raised important questions concerning the maturation of thyroglobulin (the thyroid prohormone) in certain human kindreds with congenital goiter. We have now examined affected siblings f...

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Bibliografische gegevens
Hoofdauteurs: Medeiros-Neto, G, Kim, P S, Yoo, S E, Vono, J, Targovnik, H M, Camargo, R, Hossain, S A, Arvan, P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507751/
https://ncbi.nlm.nih.gov/pubmed/8981932
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