TIPE2 (Tumor Necrosis Factor α-induced Protein 8-like 2) Is a Novel Negative Regulator of TAK1 Signal

TIPE2 (TNF-α-induced protein 8-like 2) is a novel death effector domain protein and is a negative regulator of the innate and adaptive immune response. Although it has been demonstrated that caspase-8 contributes to the negative regulation of TIPE2, the negative regulatory mechanism is not entirely...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Oho, Michitaka, Nakano, Risa, Nakayama, Ryutarou, Sakurai, Wataru, Miyamoto, Azusa, Masuhiro, Yoshikazu, Hanazawa, Shigemasa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077201/
https://ncbi.nlm.nih.gov/pubmed/27601471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733451
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