MitoNEET Deficiency Alleviates Experimental Alcoholic Steatohepatitis in Mice by Stimulating Endocrine Adiponectin-Fgf15 Axis

MitoNEET (mNT) (CDGSH iron-sulfur domain-containing protein 1 or CISD1) is an outer mitochondrial membrane protein that donates 2Fe-2S clusters to apo-acceptor proteins. In the present study, using a global mNT knock-out (mNTKO) mouse model, we investigated the in vivo functional role of mNT in the...

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Vydáno v:J Biol Chem
Hlavní autoři: Hu, Xudong, Jogasuria, Alvin, Wang, Jiayou, Kim, Chunki, Han, Yoonhee, Shen, Hong, Wu, Jiashin, You, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077187/
https://ncbi.nlm.nih.gov/pubmed/27573244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.737015
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