The European Eel NCCβ Gene Encodes a Thiazide-resistant Na-Cl Cotransporter

The thiazide-sensitive Na-Cl cotransporter (NCC) is the major pathway for salt reabsorption in the mammalian distal convoluted tubule. NCC plays a key role in the regulation of blood pressure. Its inhibition with thiazides constitutes the primary baseline therapy for arterial hypertension. However,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Moreno, Erika, Plata, Consuelo, Rodríguez-Gama, Alejandro, Argaiz, Eduardo R., Vázquez, Norma, Leyva-Ríos, Karla, Islas, León, Cutler, Christopher, Pacheco-Alvarez, Diana, Mercado, Adriana, Cariño-Cortés, Raquel, Castañeda-Bueno, María, Gamba, Gerardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Membrane Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077186/
https://ncbi.nlm.nih.gov/pubmed/27587391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742783
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