טוען...

Reversal of Phospholamban Inhibition of the Sarco(endo)plasmic Reticulum Ca(2+)-ATPase (SERCA) Using Short, Protein-interacting RNAs and Oligonucleotide Analogs

The sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) and phospholamban (PLN) complex regulates heart relaxation through its removal of cytosolic Ca(2+) during diastole. Dysfunction of this complex has been related to many heart disorders and is therefore a key pharmacological target. There are cur...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Soller, Kailey J., Yang, Jing, Veglia, Gianluigi, Bowser, Michael T.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2016
נושאים:
RNA
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076822/
https://ncbi.nlm.nih.gov/pubmed/27531746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738807
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