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LRRK2 inhibitors and their potential in the treatment of Parkinson’s disease: current perspectives

Major advances in understanding how genetics underlies Parkinson’s disease (PD) have provided new opportunities for understanding disease pathogenesis and potential new targets for therapeutic intervention. One such target is leucine-rich repeat kinase 2 (LRRK2), an enigmatic enzyme implicated in bo...

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Detalles Bibliográficos
Publicado en:Clin Pharmacol
Main Authors: Atashrazm, Farzaneh, Dzamko, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076802/
https://ncbi.nlm.nih.gov/pubmed/27799832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S102191
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