Osteopontin is produced by rat cardiac fibroblasts and mediates A(II)-induced DNA synthesis and collagen gel contraction.

Angiotensin II (AII) is a critical factor in cardiac remodeling which involves hypertrophy, fibroblast proliferation, and extracellular matrix production. However, little is known about the mechanism by which AII accelerates these responses. Osteopontin is an acidic phosphoprotein with RGD (arginine...

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Bibliografske podrobnosti
Main Authors: Ashizawa, N, Graf, K, Do, Y S, Nunohiro, T, Giachelli, C M, Meehan, W P, Tuan, T L, Hsueh, W A
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC507670/
https://ncbi.nlm.nih.gov/pubmed/8941637
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