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Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes

The protein phosphatase 2A (PP2A) subfamily of phosphatases, PP2A, PP4, and PP6, are multifunctional serine/threonine protein phosphatases involved in many cellular processes. Carboxyl methylation of the PP2A catalytic subunit (PP2Ac) C-terminal leucine is regulated by the opposing activities of leu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hwang, Juyeon, Lee, Jocelyn A., Pallas, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076511/
https://ncbi.nlm.nih.gov/pubmed/27507813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.739920
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