Age-related changes in cerebellar and hypothalamic function accompany non-microglial immune gene expression, altered synapse organization, and excitatory amino acid neurotransmission deficits

We describe age-related molecular and neuronal changes that disrupt mobility or energy balance based on brain region and genetic background. Compared to young mice, aged C57BL/6 mice exhibit marked locomotor (but not energy balance) impairments. In contrast, aged BALB mice exhibit marked energy bala...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Bonasera, Stephen J., Arikkath, Jyothi, Boska, Michael D., Chaudoin, Tammy R., DeKorver, Nicholas W., Goulding, Evan H., Hoke, Traci A., Mojtahedzedah, Vahid, Reyelts, Crystal D., Sajja, Balasrinivasa, Schenk, A. Katrin, Tecott, Laurence H., Volden, Tiffany A.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076456/
https://ncbi.nlm.nih.gov/pubmed/27689748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101040
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