Age-related changes in cerebellar and hypothalamic function accompany non-microglial immune gene expression, altered synapse organization, and excitatory amino acid neurotransmission deficits

We describe age-related molecular and neuronal changes that disrupt mobility or energy balance based on brain region and genetic background. Compared to young mice, aged C57BL/6 mice exhibit marked locomotor (but not energy balance) impairments. In contrast, aged BALB mice exhibit marked energy bala...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Bonasera, Stephen J., Arikkath, Jyothi, Boska, Michael D., Chaudoin, Tammy R., DeKorver, Nicholas W., Goulding, Evan H., Hoke, Traci A., Mojtahedzedah, Vahid, Reyelts, Crystal D., Sajja, Balasrinivasa, Schenk, A. Katrin, Tecott, Laurence H., Volden, Tiffany A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076456/
https://ncbi.nlm.nih.gov/pubmed/27689748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101040
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