G-protein alpha subunit Gi(alpha)2 mediates erythropoietin signal transduction in human erythroid precursors.
Erythropoietin induces a dose-dependent increase in cytosolic calcium in human erythroblasts that is mediated by a voltage-independent Ca2+ channel. Inhibition of this response to erythropoietin by pertussis toxin suggests involvement of guanine nucleotide-binding regulatory proteins (G-proteins). T...
Kaydedildi:
| Yayımlandı: | J Clin Invest |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878422/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118971 |
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