G-protein alpha subunit Gi(alpha)2 mediates erythropoietin signal transduction in human erythroid precursors.

Erythropoietin induces a dose-dependent increase in cytosolic calcium in human erythroblasts that is mediated by a voltage-independent Ca2+ channel. Inhibition of this response to erythropoietin by pertussis toxin suggests involvement of guanine nucleotide-binding regulatory proteins (G-proteins). T...

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Pubblicato in:	J Clin Invest
Autori principali:	Miller, B A, Bell, L, Hansen, C A, Robishaw, J D, Linder, M E, Cheung, J Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878422/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118971
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