Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro.

IL-12 is a cytokine detected in active lesions in multiple sclerosis (MS) and promotes the acquisition of a Th1 cytokine profile by CD4+ T cells. Autoreactive T cells recovered from the central nervous system of animals with experimental autoimmune encephalomyelitis (EAE), a disease model for MS, di...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Becher, B, Dodelet, V, Fedorowicz, V, Antel, J P
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507585/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8833901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118946
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