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Recombinant Guinea Pig Tumor Necrosis Factor Alpha Stimulates the Expression of Interleukin-12 and the Inhibition of Mycobacterium tuberculosis Growth in Macrophages

Tumor necrosis factor alpha (TNF-α) plays an important role in the host immune response to infection with the intracellular pathogen Mycobacterium tuberculosis. It is essential for the formation of protective tuberculous granulomas and regulates the expression of other cytokines which contribute to...

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Autores principales: Cho, Hyosun, Lasco, Todd M., Allen, Shannon Sedberry, Yoshimura, Teizo, McMurray, David N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064954/
https://ncbi.nlm.nih.gov/pubmed/15731034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1367-1376.2005
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