Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition

Using matrix elasticity and cyclic stretch have been investigated for inducing mesenchymal stromal cell (MSC) differentiation towards the smooth muscle cell (SMC) lineage but not in combination. We hypothesized that combining lineage-specific stiffness with cyclic stretch would result in a significa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rothdiener, Miriam, Hegemann, Miriam, Uynuk-Ool, Tatiana, Walters, Brandan, Papugy, Piruntha, Nguyen, Phong, Claus, Valentin, Seeger, Tanja, Stoeckle, Ulrich, Boehme, Karen A., Aicher, Wilhelm K., Stegemann, Jan P., Hart, Melanie L., Kurz, Bodo, Klein, Gerd, Rolauffs, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075785/
https://ncbi.nlm.nih.gov/pubmed/27775041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35840
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