Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology

OBJECTIVES: Current repair procedures for articular cartilage cannot restore the tissue’s original form and function because neither changes in its architectural blueprint throughout life nor the respective biological understanding is fully available. We asked whether two unique elements of human ca...

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Publicado en:Osteoarthritis Cartilage
Autores principales: Felka, Tino, Rothdiener, Miriam, Bast, Sina, Uynuk-Ool, Tatiana, Zouhair, Sabra, Ochs, Björn Gunnar, De Zwart, Peter, Stoeckle, Ulrich, Aicher, Wilhelm K, Hart, Melanie L, Shiozawa, Thomas, Grodzinsky, Alan J, Schenke-Layland, Katja, Venkatesan, Jagadeesh K, Cucchiarini, Magali, Madry, Henning, Kurz, Bodo, Rolauffs, Bernd
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907798/
https://ncbi.nlm.nih.gov/pubmed/26879798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.02.001
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