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Age increases reactive oxygen species production in macrophages and potentiates oxidative damage after spinal cord injury

Age potentiates neurodegeneration and impairs recovery from spinal cord injury (SCI). Previously, we observed that age alters the balance of destructive (M1) and protective (M2) macrophages, however, the age-related pathophysiology in SCI is poorly understood. NADPH oxidase (NOX) contributes to reac...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Zhang, B., Bailey, W. M., McVicar, A.L., Gensel, J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075497/
https://ncbi.nlm.nih.gov/pubmed/27596335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.07.029
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