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Age increases reactive oxygen species production in macrophages and potentiates oxidative damage after spinal cord injury

Age potentiates neurodegeneration and impairs recovery from spinal cord injury (SCI). Previously, we observed that age alters the balance of destructive (M1) and protective (M2) macrophages, however, the age-related pathophysiology in SCI is poorly understood. NADPH oxidase (NOX) contributes to reac...

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Bibliografiske detaljer
Udgivet i:Neurobiol Aging
Main Authors: Zhang, B., Bailey, W. M., McVicar, A.L., Gensel, J. C.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075497/
https://ncbi.nlm.nih.gov/pubmed/27596335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.07.029
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