Widespread white matter and conduction defects in PSEN1-related spastic paraparesis

The mechanisms underlying PSEN1 mutation-associated spastic paraparesis (SP) are not clear. We compared diffusion and volumetric magnetic resonance measures between 3 persons with SP associated with the A431E mutation and 7 symptomatic persons with PSEN1 mutations without SP matched for symptom dura...

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Publicado en:Neurobiol Aging
Autores principales: Soosman, Steffan K., Joseph-Mathurin, Nelly, Braskie, Meredith N., Bordelon, Yvette M., Wharton, David, Casado, Maria, Coppola, Giovanni, McCallum, Holly, Nuwer, Marc, Coutin-Churchman, Pedro, Apostolova, Liana G., Benzinger, Tammie, Ringman, John M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075491/
https://ncbi.nlm.nih.gov/pubmed/27614114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.07.030
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