Diffusion Tensor Imaging in PSEN1-Related Spastic Paraparesis Reveals Widespread White Matter Abnormalities

OBJECTIVE: To investigate white matter changes in familial Alzheimer's disease (FAD) patients with spastic paraparesis (SP) using diffusion tensor imaging (DTI). BACKGROUND: Though FAD due to PSEN1 mutations typically recapitulates late onset AD, it can have unusual clinical features including...

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Detalhes bibliográficos
Main Authors: Soosman, Steffan K, Braskie, Meredith N, Alger, Jeffry, Bordelon, Yvette M, Wharton, David, Ringman, John M
Formato: Artigo
Idioma:Inglês
Publicado em: University Clinical, Education & Research Associate (UCERA) 2014
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Abstract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175937/
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