Neutrophil-neutrophil interactions under hydrodynamic shear stress involve L-selectin and PSGL-1. A mechanism that amplifies initial leukocyte accumulation of P-selectin in vitro.

Leukocytes attach to and roll on inflamed endothelium and on leukocyte monolayers that form on the endothelial cells. Leukocyte-leukocyte interactions occurring under hydrodynamic shear stress are mediated by binding of L-selectin to unknown sialomucin-like glycoproteins. We show that purified neutr...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Walcheck, B, Moore, K L, McEver, R P, Kishimoto, T K
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1996
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118888
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