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High-resolution views of TRPV1 and their implications for the TRP channel superfamily

The first high-resolution structures of a near-full-length TRP channel were recently described, structures of the noxious heat receptor TRPV1 in the absence or presence of vanilloid agonists and a spider toxin. Here we briefly review the salient features, including the overall architecture, agonist...

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Detalhes bibliográficos
Publicado no:Handb Exp Pharmacol
Main Authors: Hellmich, Ute A., Gaudet, Rachelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075239/
https://ncbi.nlm.nih.gov/pubmed/24961977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-05161-1_11
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