Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses.

We have characterized the progressive stages of chronic intestinal inflammation that develops spontaneously in specific pathogen-free (SPF) mice with a targeted disruption in the IL-10 gene (IL-10-/-). Our longitudinal studies showed that inflammatory changes first appear in the cecum, ascending and...

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Detalhes bibliográficos
Main Authors: Berg, D J, Davidson, N, Kühn, R, Müller, W, Menon, S, Holland, G, Thompson-Snipes, L, Leach, M W, Rennick, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507517/
https://ncbi.nlm.nih.gov/pubmed/8770874
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