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Interleukin-10 Is a Natural Suppressor of Cytokine Production and Inflammation in a Murine Model of Allergic Bronchopulmonary Aspergillosis
We have used interleukin-10 (IL-10) gene knockout mice (IL-10(−/−)) to examine the role of endogenous IL-10 in allergic lung responses to Aspergillus fumigatus Ag. In vitro restimulated lung cells from sensitized IL-10(−/−) mice produced exaggerated amounts of IL-4, IL-5, and interferon-γ (IFN-γ) co...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2196229/ https://ncbi.nlm.nih.gov/pubmed/9091582 |
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