Association between Type A blaZ Gene Polymorphism and Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus

Some proportion of type A blaZ gene-positive methicillin-susceptible Staphylococcus aureus strains exhibit the cefazolin inoculum effect (CIE). The type A blaZ gene was divided into two groups by single nucleotide polymorphisms (SNPs) at Ser226Pro and Cys229Tyr. The median cefazolin MICs at a high i...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Lee, Sun Hee, Park, Wan Beom, Lee, Shinwon, Park, Sohee, Kim, Shin Woo, Lee, Jong-Myung, Chang, Hyun Ha, Kwon, Ki Tae, Choe, Pyoeng Gyun, Kim, Nam Joong, Kim, Hong Bin, Oh, Myoung-Don
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075110/
https://ncbi.nlm.nih.gov/pubmed/27572417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01517-16
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