Prevalence of a Cefazolin Inoculum Effect Associated with blaZ Gene Types among Methicillin-Susceptible Staphylococcus aureus Isolates from Four Major Medical Centers in Chicago

The efficacy of cefazolin with high-inoculum methicillin-susceptible Staphylococcus aureus (MSSA) infections remains in question due to therapeutic failure inferred as being due to an inoculum effect (InE). This study investigated the local prevalence of a cefazolin InE (CInE) and its association wi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wang, Sheila K., Gilchrist, Annette, Loukitcheva, Anastasia, Plotkin, Balbina J., Sigar, Ira M., Gross, Alan E., O'Donnell, J. Nicholas, Pettit, Natasha, Buros, Amy, O'Driscoll, Tristan, Rhodes, Nathaniel J., Bethel, Cindy, Segreti, John, Charnot-Katsikas, Angella, Singh, Kamaljit, Scheetz, Marc H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105856/
https://ncbi.nlm.nih.gov/pubmed/29891607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00382-18
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