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Transposon-Sequencing Analysis Unveils Novel Genes Involved in the Generation of Persister Cells in Uropathogenic Escherichia coli

Persister cells are highly tolerant to different antibiotics and are associated with relapsing infections. In order to understand this phenomenon further, we exposed a transposon library to a lethal concentration of ampicillin, and mutants that survived were identified by transposon sequencing (Tn-S...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Molina-Quiroz, Roberto C., Lazinski, David W., Camilli, Andrew, Levy, Stuart B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075105/
https://ncbi.nlm.nih.gov/pubmed/27550350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01617-16
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