Rapid Detection of FKS-Associated Echinocandin Resistance in Candida glabrata

A novel and highly accurate diagnostic assay platform was established for rapid identification of FKS mutations associated with echinocandin resistance in Candida glabrata. The assay platform uses allele-specific molecular beacon and DNA melt analysis following asymmetric PCR. A dual assay for FKS1...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Zhao, Yanan, Nagasaki, Yoji, Kordalewska, Milena, Press, Ellen G., Shields, Ryan K., Nguyen, M. Hong, Clancy, Cornelius J., Perlin, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075061/
https://ncbi.nlm.nih.gov/pubmed/27550360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01574-16
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