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Glucose tolerance in mice is linked to the dose of the p53 transactivation domain

The tumor suppressor p53 has a critical role in maintenance of glucose homeostasis. Phosphorylation of Ser(18) in the transaction domain of p53 controls the expression of Zpf385a, a zinc finger protein that regulates adipogenesis and adipose function. Mice with a mutation in p53Ser(18) exhibit reduc...

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Detalhes bibliográficos
Publicado no:Endocr Res
Main Authors: Franck, Debra, Tracy, Laura, Armata, Heather L., Delaney, Christine L., Jung, Dae Young, Ko, Hwi Jin, Ong, Helena, Kim, Jason K., Scrable, Heidi, Sluss, Hayla K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074905/
https://ncbi.nlm.nih.gov/pubmed/23102272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07435800.2012.735735
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