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Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq

A substantial number of mutations have been identified in voltage-gated sodium channel genes that result in various forms of human epilepsy. SCN1A mutations result in a spectrum of severity ranging from mild febrile seizures to Dravet syndrome, an infant-onset epileptic encephalopathy. Dravet syndro...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Hawkins, Nicole A., Zachwieja, Nicole J., Miller, Alison R., Anderson, Lyndsey L., Kearney, Jennifer A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074504/
https://ncbi.nlm.nih.gov/pubmed/27768696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006398
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