Intranasal Opioid Administration in Rhesus Monkeys: PET Imaging and Antinociception

The goal of this study was to evaluate the effects of intranasally administered opioids in rhesus monkeys using the tail-withdrawal assay, and to correlate these effects with measures of receptor occupancy using positron emission tomography (PET) imaging. Initial experiments characterized the antino...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Saccone, Phillip A., Lindsey, Angela M., Koeppe, Robert A., Zelenock, Kathy A., Shao, Xia, Sherman, Phillip, Quesada, Carole A., Woods, James H., Scott, Peter J. H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Behavioral Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074481/
https://ncbi.nlm.nih.gov/pubmed/27625351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.235192
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