Duloxetine Inhibits Microglial P2X4 Receptor Function and Alleviates Neuropathic Pain after Peripheral Nerve Injury

P2X4 receptors (P2X4R) are a family of ATP-gated non-selective cation channels. We previously demonstrated that activation of P2X4R in spinal microglia is crucial for neuropathic pain, a highly debilitating chronic pain condition, suggesting that P2X4R is a potential therapeutic target for treating...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yamashita, Tomohiro, Yamamoto, Shota, Zhang, Jiaming, Kometani, Miho, Tomiyama, Daisuke, Kohno, Keita, Tozaki-Saitoh, Hidetoshi, Inoue, Kazuhide, Tsuda, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074465/
https://ncbi.nlm.nih.gov/pubmed/27768754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165189
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados