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Transfer of Electrophilic NH Using Convenient Sources of Ammonia: Direct Synthesis of NH Sulfoximines from Sulfoxides

A new system for NH transfer is developed for the preparation of sulfoximines, which are emerging as valuable motifs for drug discovery. The protocol employs readily available sources of nitrogen without the requirement for either preactivation or for metal catalysts. Mixing ammonium salts with diac...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Zenzola, Marina, Doran, Robert, Degennaro, Leonardo, Luisi, Renzo, Bull, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074267/
https://ncbi.nlm.nih.gov/pubmed/27126053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602320
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