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Transfer of Electrophilic NH Using Convenient Sources of Ammonia: Direct Synthesis of NH Sulfoximines from Sulfoxides

A new system for NH transfer is developed for the preparation of sulfoximines, which are emerging as valuable motifs for drug discovery. The protocol employs readily available sources of nitrogen without the requirement for either preactivation or for metal catalysts. Mixing ammonium salts with diac...

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Bibliografische gegevens
Gepubliceerd in:Angew Chem Int Ed Engl
Hoofdauteurs: Zenzola, Marina, Doran, Robert, Degennaro, Leonardo, Luisi, Renzo, Bull, James A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074267/
https://ncbi.nlm.nih.gov/pubmed/27126053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602320
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