Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis.

Polymyositis (PM) and dermatomyositis (DM) are the prototypical inflammatory diseases of skeletal muscle. In PM, CD8+ T cells invade and destroy muscle fibers, whereas humoral effector mechanisms prevail in DM. We studied the expression of the cytotoxic mediator perforin in inflammatory cells in PM...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Goebels, N, Michaelis, D, Engelhardt, M, Huber, S, Bender, A, Pongratz, D, Johnson, M A, Wekerle, H, Tschopp, J, Jenne, D, Hohlfeld, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507387/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118749
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