Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis.

Polymyositis (PM) and dermatomyositis (DM) are the prototypical inflammatory diseases of skeletal muscle. In PM, CD8+ T cells invade and destroy muscle fibers, whereas humoral effector mechanisms prevail in DM. We studied the expression of the cytotoxic mediator perforin in inflammatory cells in PM...

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Autors principals: Goebels, N, Michaelis, D, Engelhardt, M, Huber, S, Bender, A, Pongratz, D, Johnson, M A, Wekerle, H, Tschopp, J, Jenne, D, Hohlfeld, R
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC507387/
https://ncbi.nlm.nih.gov/pubmed/8675705
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