Responses of single germinal-center B cells in T-cell-dependent microculture.
B cells purified from the germinal centers (GCs) of murine Peyer's patches can be stimulated in a clonal microculture containing helper T cells and dendritic cells to divide and secrete immunoglobulin. Intraclonal isotype switching occurs, and a variety of immunoglobulin isotypes, including IgA, is...
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| 发表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
National Academy of Sciences
1991
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| 主题: | |
| 在线阅读: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1824722/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.11 |
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