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Responses of single germinal-center B cells in T-cell-dependent microculture.

B cells purified from the germinal centers (GCs) of murine Peyer's patches can be stimulated in a clonal microculture containing helper T cells and dendritic cells to divide and secrete immunoglobulin. Intraclonal isotype switching occurs, and a variety of immunoglobulin isotypes, including IgA, is...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: George, A, Cebra, J J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50737/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1824722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.11
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