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Absence of loss of heterozygosity of BRCA1 in a renal tumor from a BRCA1 germline mutation carrier
BRCA1 functions as a tumor suppressor gene and germline and somatic mutations in this gene have been shown to be associated with many types of cancer. We report the first tumor study of renal cell carcinoma in a carrier of the deleterious BRCA1 mutation-c.68_69delAG.
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| Publicado en: | Fam Cancer |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073794/ https://ncbi.nlm.nih.gov/pubmed/23086583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-012-9572-0 |
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