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Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase.

Deficiency of plasma platelet-activating factor (PAF) acetylhydrolase is an autosomal recessive syndrome that has been associated with severe asthma in Japanese children. Acquired deficiency has been described in several human diseases usually associated with severe inflammation. PAF acetylhydrolase...

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Bibliographic Details
Main Authors: Stafforini, D M, Satoh, K, Atkinson, D L, Tjoelker, L W, Eberhardt, C, Yoshida, H, Imaizumi, T, Takamatsu, S, Zimmerman, G A, McIntyre, T M, Gray, P W, Prescott, S M
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC507371/
https://ncbi.nlm.nih.gov/pubmed/8675689
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