A mouse model of gyrate atrophy of the choroid and retina. Early retinal pigment epithelium damage and progressive retinal degeneration.

Gyrate atrophy (GA) of the choroid and retina is a blinding chorioretinal degeneration caused by deficiency of ornithine delta-aminotransferase (OAT). The phenotype of GA is characterized by progressive concentric reduction of the visual fields and ornithine accumulation. To understand better the pa...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Wang, T, Milam, A H, Steel, G, Valle, D
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507368/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118730
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