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Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice.

The regulation of liver apolipoprotein (apo) A-I gene expression by fibrates was studied in human apo A-I transgenic mice containing a human genomic DNA fragment driving apo A-I expression in liver. Treatment with fenofibrate (0.5% wt/wt) for 7 d increased plasma human apo A-I levels up to 750% and...

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書誌詳細
主要な著者: Berthou, L, Duverger, N, Emmanuel, F, Langouët, S, Auwerx, J, Guillouzo, A, Fruchart, J C, Rubin, E, Denèfle, P, Staels, B, Branellec, D
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC507325/
https://ncbi.nlm.nih.gov/pubmed/8647932
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