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Risk factor SORL1: from genetic association to functional validation in Alzheimer’s disease

Alzheimer’s disease (AD) represents one of the most dramatic threats to healthy aging and devising effective treatments for this devastating condition remains a major challenge in biomedical research. Much has been learned about the molecular concepts that govern proteolytic processing of the amyloi...

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Détails bibliographiques
Publié dans:Acta Neuropathol
Auteurs principaux: Andersen, Olav M., Rudolph, Ina-Maria, Willnow, Thomas E.
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073117/
https://ncbi.nlm.nih.gov/pubmed/27638701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1615-4
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