Increased microvascular permeability in mice lacking Epac1 (Rapgef3)

AIM: Maintenance of the blood and extracellular volume requires tight control of endothelial macromolecule permeability, which is regulated by cAMP signalling. This study probes the role of the cAMP mediators rap guanine nucleotide exchange factor 3 and 4 (Epac1 and Epac2) for in vivo control of mic...

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Dades bibliogràfiques
Publicat a:Acta Physiol (Oxf)
Autors principals: Kopperud, R. K., Rygh, C. Brekke, Karlsen, T. V., Krakstad, C., Kleppe, R., Hoivik, E. A., Bakke, M., Tenstad, O., Selheim, F., Lidén, Å., Madsen, L., Pavlin, T., Taxt, T., Kristiansen, K., Curry, F.‐R. E., Reed, R. K., Døskeland, S. O.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Cardiovascular Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073050/
https://ncbi.nlm.nih.gov/pubmed/27096875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12697
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