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Increased microvascular permeability in mice lacking Epac1 (Rapgef3)
AIM: Maintenance of the blood and extracellular volume requires tight control of endothelial macromolecule permeability, which is regulated by cAMP signalling. This study probes the role of the cAMP mediators rap guanine nucleotide exchange factor 3 and 4 (Epac1 and Epac2) for in vivo control of mic...
Guardado en:
Publicado en: | Acta Physiol (Oxf) |
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Autores principales: | , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073050/ https://ncbi.nlm.nih.gov/pubmed/27096875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12697 |
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