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Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma
BACKGROUND: Epithelial barrier dysfunction and increased permeability may contribute to antigen sensitization and disease progression in asthma. Claudin-18.1 is the only known lung-specific tight junction protein, but its contribution to airway barrier function or asthma is unclear. OBJECTIVES: To t...
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| Опубликовано в: : | J Allergy Clin Immunol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073041/ https://ncbi.nlm.nih.gov/pubmed/27215490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.02.035 |
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