Claudin-18 Deficiency Results in Alveolar Barrier Dysfunction and Impaired Alveologenesis in Mice

Claudins are a family of transmembrane proteins that are required for tight junction formation. Claudin (CLDN)-18.1, the only known lung-specific tight junction protein, is the most abundant claudin in alveolar epithelial type (AT) 1 cells, and is regulated by lung maturational agonists and inflamma...

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Detalhes bibliográficos
Main Authors: LaFemina, Michael J., Sutherland, Katherine M., Bentley, Trevor, Gonzales, Linda W., Allen, Lennell, Chapin, Cheryl J., Rokkam, Deepti, Sweerus, Kelly A., Dobbs, Leland G., Ballard, Philip L., Frank, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189483/
https://ncbi.nlm.nih.gov/pubmed/24787463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0456OC
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