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The double edged sword of the immune response: mutational analysis of a murine anti-pneumococcal, anti-DNA antibody.

Anti-double-stranded (ds) DNA antibodies are not only an important diagnostic marker for SLE, but also play an important role in tissue injury. Microbial antigen may be a stimulus for the production of these antibodies. We isolated 99D.7E, an IgG2b monoclonal antibody from a nonautoimmune BALB/c mou...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Putterman, C, Limpanasithikul, W, Edelman, M, Diamond, B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8636404/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118666
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